ACE2 Expression in Kidney and Testis May Cause Kidney and Testis Damage After 2019-nCoV Infection
https://www.medrxiv.org/content/10.1101/2020.02.12.20022418v1
2019-nCoV °¨¿° ÈÄ
Results of immunohistochemistry (IHC) also indicated that the expression level of ACE2 protein is significantly higher in the kidney,
especially in renal tubular cells, although the mRNA expression level is not such high
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Unexpectedly, we also found that ACE2 expresses quite highly in testicular cells. The protein and
mRNA expression of ACE2 in the testes is almost the highest in the body.
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°íȯ¿¡¼ ACE2ÀÇ mRNA ¹ßÇöÀº ½Åü¿¡¼ °ÅÀÇ °¡Àå ³ô½À´Ï´Ù.
These results indicate that testicular cells are the potential targets of 2019-nCoV.
ÀÌ °á°ú´Â °íȯ ¼¼Æ÷°¡ 2019-nCoVÀÇ ÀáÀçÀû ¸ñÇ¥ÀÓÀ» ³ªÅ¸³À´Ï´Ù
(2019-nCoV) - infected pneumonia patients are young adults and even children, so the potential
testicular damage caused by the virus may exist as a late complication.
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